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Researcher Bios
J  oachim Kohn, PhD Director, RCCC Rutgers, the State University of New Jersey Director, New Jersey Center for Biomaterials (njbiomaterials.org) Board of Governors Professor, Department of Chemistry and Chemical Biology Adjunct Associate Professor of Orthopaedics, New Jersey Medical School JOACHIM KOHN is a pioneer in the use of combinatorial and computational methods for the optimization of biomaterials for specific medical applications and is known for his seminal work on "pseudo-poly(amino acid)s". He has published more than 200 scientific manuscripts, holds 40 patents, has spun-off three start-up companies, and has twice received the annual Thomas Alva Edison Patent Award for best patent in New Jersey. Back to top
Linda M. Graham, MD Department of Vascular Surgery LINDA M. GRAHAM is a practicing vascular surgeon with an active research laboratory. Her NIH-funded research focuses on vascular wall biology and graft healing. She has developed methods to seed cells onto prosthetic scaffolds to produce tissue lined vascular grafts. She has published over 100 journal articles and book chapters.
Joseph M. Rosen, MD Dartmouth College/Hitchcock Medical Center  Daniel G. Anderson, PhD Massachusetts Institute of Technology Research Associate, David H. Koch Institute for Integrative Cancer Research (http://web.mit.edu/ki/) DANIEL G. ANDERSON pioneered the use of robotic methods for the development of smart biomaterials for drug delivery and tissue engineering. He has developed robotic technology that allows rapid synthesis, formulation, analysis, and biological testing of large libraries of biomaterials for use in medical devices, cell therapy and drug delivery, resulting in publication of over 80 papers and pending patents. Back to top  Steven T. Boyce, PhD University of Cincinnati Professor, Department of Surgery, College of Medicine Adjunct Professor, Department of Biomedical Engineering, College of Engineering Senior Investigator, Research Department Shriners Burns Hospital, Cincinnati, Ohio STEVEN BOYCE has made numerous discoveries which have led to regulated growth of skin cells in combination with degradable biopolymer implants. Preclinical studies based on his work have demonstrated formation of skin barrier and blood vessels, and restoration of pigmentation. Dr. Boyce has also received numerous patents, and founded two start-up companies. Back to top  Richard A. F. Clark, MDStony Brook University Director, Center of Tissue Engineering Professor, Department of Biomedical Engineering, Dermatology Adjunct Professor, Department of Medicine RICHARD A. F. CLARK has extensive experience in wound healing and skin disorders. He has made seminal observations regarding the sources and significance of fibronectin protein in wounds and wound healing, including the discovery of bioactive peptides within the fibronectin structure that enhance the activity of growth factors and act as survival factors for tissue cells. Dr. Clark is the scientific founder of two start-up companies. Back to top  Kathleen A. Derwin, PhD Cleveland Clinic Assistant Staff, Department of Biomedical Engineering, Lerner Research Institute, and Joint Appointee, Department of Orthopaedic Surgery Assistant Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University Adjunct Assistant Professor, Department of Biomedical Engineering, Case Western Reserve University KATHLEEN A. DERWIN’s research focuses on various aspects of understanding the causes and improving the treatment of musculoskeletal soft tissue injuries. Her multidisciplinary team has developed natural, mechanically robust extracellular matrix scaffolds for rotator cuff repair, novel model systems for evaluating scaffold-based technologies, and real-time imaging techniques for quantifying the progression of healing in living systems. Back to top  Michael G. Dunn, PhD University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School Associate Professor of Orthopaedic Surgery and Founding Director, Orthopaedic Research Laboratories Faculty Member, Rutgers-UMDNJ Joint Graduate Program in Biomedical Engineering MICHAEL G. DUNN’s principal research interests are in tissue engineering approaches for regeneration and reconstruction of musculoskeletal soft tissues. His collaborations with Dr. Gatt focus on polymer and collagen scaffolds for ligament and meniscus implants. Back to top  Charles J. Gatt, MD University of Medicine and Dentistry of New Jersey Chairman, Department of Orthopaedic Surgery, Adjunct Faculty, School of Biomedical Engineering, Rutgers University, New Brunswick, New Jersey CHARLES J. GATT, JR. is an orthopaedic surgeon specializing in sports medicine. Dr. Gatt’s research interests include tissue engineering and allograft (grafts from other individuals) science, including development of scaffolds for the treatment of ligament and meniscal injuries. His work has evaluated the effects of donor age and gender on mechanical properties of allografts and the effects of growth factors on allograft incorporation. Back to top  Stanton L. Gerson, MD Case Western Reserve University Asa and Patricia Shiverick Professor Director of the Case Comprehensive Cancer Center and Ireland Cancer Center Director of the Ohio Wright Center for Stem Cell and Regenerative Medicine at Case School of Medicine and University Hospitals Case Medical Center, Cleveland, Ohio Dr. Gerson has been active in developing therapeutic programs that use stem cells to treat hematologic malignancies. His research interests are in the areas of stem cells and DNA repair. His research has generated seven patents in the area of gene therapy and cancer drug development that have been licensed to three companies. Back to top  Linda G. Griffith, PhD Massachusetts Institute of Technology Director of MIT Biotech/Pharma Engineering Center School of Engineering Teaching Innovation Professor Department of Biological Engineering and Department of Mechanical Engineering LINDA G. GRIFFITH conducts research in biomaterials and devices for tissue and organ regeneration combining molecular design and synthesis of biomaterials with design and synthesis of macroscopic 3-D devices for therapeutic and in vitro use. Dr. Griffith, a MacArthur Foundation Fellow, is a co-founder of Therics, Inc. and has served as consultant or advisory board member for several tissue engineering and pharmaceutical companies. Back to top  Scott A. Guelcher, PhD Vanderbilt University Assistant Professor, Department of Chemical Engineering SCOTT A. GUELCHER’s research interests are in the design and development of biodegradable polyurethane scaffolds, composites, and delivery systems for bone regeneration to meet the needs of the targeted clinical application. His research team has prepared biomaterials with enhanced biological and mechanical properties by combining the polymers with allograft bone, growth factors, and antibiotics. He is a co-inventor on 15 US patents and pending applications. Back to top  Jeffrey O. Hollinger, DDS, PhD Carnegie Mellon University Director, Bone Tissue Engineering Center Professor, Biomedical Engineering Department JEFFREY O. HOLLINGER’s research interests are in bone regeneration, including regeneration of osseous components of the cranio-mandibular facial complex. He is also engaged with several industrial groups that emphasize bone regenerative therapeutics. Dr. Hollinger has over 250 peer-reviewed publications, abstracts, book chapters and books. He retired in 1993 from the US Army as a Colonel after serving 20 years of active duty. Back to top  Adam J. Katz, MD, FACS University of Florida Associate Professor, Division of Plastic and Reconstructive Surgery Director of Plastic Surgery Research Director of Clinical Trials, Department of Surgery ADAM J. KATZ is a clinically active plastic surgeon. Dr. Katz helped pioneer the conception, detection, description, and early characterization of multipotent stem cells derived from human adipose tissue, while a surgical resident at University of Pittsburgh Medical Center. Dr. Katz is the author of multiple issued and pending patents related to adipose-derived cells, and has helped found several companies based on university research. Back to top  Robert S. Langer, ScD Massachusetts Institute of Technology Germeshausen Professor of Chemical and Biomedical Engineering, Department of Chemical Engineering ROBERT S. LANGERS’s research interests includes drug delivery, biotechnology, immobilized enzymes, and biomedical engineering. His specialty is the study and development of polymers to deliver drugs, particularly genetically engineered proteins and DNA. Among Dr. Langer's more than 300 active and more than 300 pending patents, many have been licensed or sublicensed to over 220 pharmaceutical, chemical, biotechnology and medical device companies. Back to top  Thomas A. Mustoe, MD Northwestern University Professor and Chief, Division of Plastic Surgery Feinberg School of Medicine Professor Director of Wound Healing Research Laboratory THOMAS A. MUSTOE’s research involves wound healing with a focus on utilizing animal models to elucidate basic mechanisms of healing and scarring. He has also had multiple collaborations with biotechnology and pharmaceutical companies and carried out FDA sponsored clinical trials in scarring and wound healing. He has co-authored more than 150 peer-reviewed papers, with multiple chapters, and invited articles; he also has an active clinical practice. Back to top  George F. Muschler, MDCleveland Clinic Staff Surgeon, Department of Orthopaedic Surgery Director, Orthopaedic Research Center and the Clinical Tissue Engineering Center (www.ctecohio.org) Vice-Chairman, Department of Biomedical Engineering Vice-Chairman for Research, Orthopaedic and Rheumatologic Institute GEORGE F. MUSCHLER specializes in reconstructive Orthopaedic Surgery and has devoted his career to advancing patient care through basic and clinical research. His primary research areas are the harvest, processing and transplantation of adult connective tissue stem cells and progenitor cells (CTPs) for treatment of fractures and problems of degenerative joints; the effects of aging and osteoporosis on CTPs; and optimizing assays for CTPs and other stem cells. Back to top  Timur P. Sarac, MD Cleveland Clinic Staff Vascular Surgeon, Cleveland Clinic Department of Vascular Surgery Associate Professor, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University TIMUR P. SARAC is a surgeon and the inventor of tissue lined stent technology among several vascular technologies. He is a retired Major in the United States Army Reserves and was awarded an Achievement Medal during Operation Iraqi Freedom /Enduring Freedom for his innovative endovascular treatment of injured soldiers. Back to top  Maria Z. Siemionow, MD, PhD Cleveland Clinic Director, Plastic Surgery Research, Department of Plastic Surgery Head, Microsurgery Training, Microsurgery Laboratory of the Department of Plastic Surgery Professor of Surgery, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH MARIA SIEMIONOW is an expert surgeon with interests and expertise including microsurgery, hand surgery, peripheral nerve surgery, transplantation, and microcirculation. Her research focuses on conducting composite tissue allograft transplantation without the need for lifelong immunosuppression. She was the first physician in the world to receive institutional approval for composite facial allograft (donor graft) transplantation surgery. Back to top  Cathryn A. Sundback, PhD Massachusetts General Hospital/Harvard University Director, Laboratory for Tissue Engineering and Organ Fabrication CATHRYN SUNDBACK’s research focuses on the application of biomaterials for tissue engineering of limb tissues, particularly peripheral nerve, skeletal muscle, and bone. She has developed neural guidance conduits to repair peripheral nerve injuries with improved return of function, resulting in numerous publications and pending patents. She is currently developing clinically translatable models to engineer functional skeletal muscle tissue and vascularized bone. Back to top  Joseph P. Vacanti, MD Massachusetts General Hospital/Harvard University John Homans Professor of Surgery Chief, Department of Pediatric Surgery, Massachusetts General Hospital (MGH) Surgeon-in-Chief, MGH Hospital for Children Co-Director, Center for Regenerative Medicine, MGH Director, Laboratory for Tissue Engineering and Organ Fabrication, MGH Chief, Pediatric Transplantation, MGH JOSPEH P. VACANTI has been working in the field of tissue engineering since its beginnings in the early 1980s - a mission that stems from his long-held interest in solving the problem of organ shortages. His approach to regenerating tissues involves a scaffold made of an artificial, biodegradable polymer, seeding it with living cells, and bathing it in growth factors. He has authored over 265 original reports, 62 book chapters and over 430 abstracts. Dr. Vacanti has 75 patents or patents pending in the United States, Canada, Europe, and Japan. Back to top  Anthony Windebank, MD Mayo Clinic Professor of Neurology, Mayo Medical School ANTHONY WINDEBANK’s major areas of research are repair and regeneration after spinal cord injury, stem cell treatment of motor neuron disease, and the mechanism of neuronal cell death caused by chemotherapeutic agents. His approach includes studies of both animal and tissue culture models of neuronal death and regeneration. Back to top  Michael J. Yaszemski, MD, PhD, Brig Gen USAF Mayo Clinic Professor of Orthopedics and Biomedical Engineering Director, Tissue Engineering and Biomaterials Laboratory MICHAEL J. YASZEMSKI‘s clinical practice encompasses spinal surgery, with a focus on the resection and reconstruction of spino-pelvic tumors. His research interests are in the synthesis and characterization of novel degradable polymers for use in bone, cartilage, and neural tissue regeneration. From July to September 2006, he deployed as Deputy Commander, 332nd Medical Group at the Air Force Theater Hospital in Balad, Iraq. Back to top
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